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Bespak is seeking permission to expand its medical devices factory in King's Lynn with two new production facilities totalling 110,000 sq ft, with the creation of 200 jobs.
Bespak is seeking permission from West Norfolk Council to build a new £1m inhalers factory at its site in King's Lynn.
Bespak has bought Decorpart, the Nelson-based metal packaging company with more than 200 staff, out of administration, and the business has been renamed Integrated Aluminium Components.
Bespak is to acquire Emergent Respiratory Products, the US supplier of breathing equipment, for up to £19m.
Bespak is to acquire King Systems Corporation, the US supplier of disposable face masks and airway tubes, for £54m.
Bespak is looking to spend up to £15m on acquisitions to expand its nasal drug delivery business and develop new products.
Bespak is in discussions to sell its King's Lynn-based personal care business, which employs 70 people, as part of a strategy to focus on the development of its drug delivery business.